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Genome sequence of the medicinal and ornamental plant Digitalis purpurea reveals the molecular basis of flower color variation

Wolff, K.; Friedhoff, R.; Horz, J. M.; Pucker, B.

2024-02-15 plant biology
10.1101/2024.02.14.580303 bioRxiv
Show abstract

Digitalis purpurea (foxglove) is a widely distributed ornamental plant. Here, we present a long read sequencing-based genome sequence of a magenta flowering D. purpurea plant and a corresponding prediction of gene models. The high assembly continuity is indicated by the N50 of 4.3 Mbp and the completeness is supported by discovery of about 96% complete BUSCO genes. This genomic resource paves the way for an in-depth investigation of the flower pigmentation of D. purpurea. Structural genes of the anthocyanin biosynthesis and the corresponding transcriptional regulators were identified. The comparison of magenta and white flowering plants revealed a large insertion in the anthocyanidin synthase gene in white flowering plants that most likely renders this gene non-functional and could explain the loss of anthocyanin pigmentation. Furthermore, we found a large insertion in the DpTFL1/CEN gene to be likely responsible for the development of large terminal flowers.

Published in BMC Genomics (predicted rank #1) · training set

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