Neutrophil extracellular trap formation linked to idiopathic pulmonary fibrosis severity and survival

2024-01-25 respiratory medicine Title + abstract only

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BackgroundIdiopathic pulmonary fibrosis (IPF) leads to progressive loss of lung function and mortality. Understanding mechanisms and markers of lung injury in IPF is paramount to improving outcomes for these patients. Despite the lack of systemic involvement in IPF, many analyses focus on identifying circulating prognostic markers. Using a proteomic discovery method followed by ELISA validation in multiple IPF lung compartments and cohorts we explored novel markers of IPF survival. MethodsIn ou...