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In major depression, complex intersections between adverse childhood experiences and negative life events impact neuroticism, brooding, suicidal tendencies, insomnia, and cognitive interference.

2024-01-07 psychiatry and clinical psychology Title + abstract only
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BackgroundThere is evidence that adverse childhood experiences (ACEs) and negative life events (NLEs) are associated with major depression (MDD). PurposeTo determine whether ACEs affect all features of mild MDD, including suicidal tendencies, brooding, neuroticism, insomnia, cognitive deficits, severity of depression and anxiety, and cognitive deficits, and whether NLEs mediate these effects. Patients and methodsThis study examines a cohort of 118 academic students, namely 74 students who sati...

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