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Multi-phase, multi-ethnic GWAS uncovers putative loci in predisposition to human sprint performance, health and disease

2023-12-09 sports medicine Title + abstract only
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The genetic underpinnings of elite sprint performance remain largely elusive. For the first time, we uncovered rs10196189 (GALNT13) in the cross-ancestry, genome-wide analysis of elite sprint and power-oriented athletes and their controls from Jamaica, the USA, and Japan, and replicated this finding in two independent cohorts of elite European athletes (meta-analysis P < 5E-08). We identified statistically significant and borderline associations for cross-ancestry and ancestry specific loci in G...

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