Spatial Metabolomics co-registered with Multiplex Phenotyping for the Evaluation of Human Kidney Tissue
Zickuhr, G. M.; Um, I. H.; Laird, A.; Harrison, D. J.; Dickson, A. L.
Show abstract
A workflow has been evaluated that utilises a single tissue section to obtain spatially co-registered, molecular, and phenotypical information suitable for AI-enabled analysis. The impact of varying DESI-MSI conditions (e.g., temperature, scan rate, acquisition time) on the detection of small molecules and on tissue quality for integration into typical clinical pathology workflows assessed in human kidney.
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