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Early Hyperoxaemia and 2-year Outcomes in Infants with Hypoxic-ischemic Encephalopathy- a Secondary Analysis of the Infant Cooling Evaluation (ICE) trial
2023-08-28
pediatrics
Title + abstract only
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Objective(s)To determine the causal relationship between exposure to early hyperoxaemia and death/disability in infants with hypoxic-ischemic encephalopathy (HIE). Study designWe analyzed data from the Infant Cooling Evaluation (ICE) trial that enrolled newborns [≥]35 weeks gestation with moderate-severe HIE, randomly allocated to hypothermia or normothermia. The primary outcome was death or major sensorineural disability at 2 years. We included infants with arterial pO2 measured within 2 h ...
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