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Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana

Eger, E.; Homeier-Bachmann, T.; Adade, E.; Dreyer, S.; Heiden, S. E.; Tawiah, P. O.; Sylverken, A. A.; Knauf, S.; Schaufler, K.

2023-08-04 microbiology
10.1101/2023.08.04.551947 bioRxiv
Show abstract

This study investigated the presence of extended-spectrum {beta}-lactamase-producing Enterobacterales in selected surface waters in the Ashanti Region in Ghana. Subsequent genomic analysis revealed that one-fifth of the isolates were genotypically carbapenem-resistant. Phenotypic susceptibility testing not only confirmed their carbapenem resistance, but also uncovered two cefiderocol-resistant isolates.

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