The effect of intercellular medium salinity on the dielectric constant of cell membranes and the excitation thresholds of the action potential
Shneider, M.; Pekker, M.
Show abstract
A mechanism for axon swelling and subsequent compression in the area of action potential passage is considered. It is shown that the dynamics of changes in the radius of the axon during the passage of the action potential can be explained by changes in osmotic pressure. Axon swelling occurs at the leading edge of the action potential when Na+ ions flow from the extracellular electrolyte into the intracellular space, and subsequent compression occurs at the trailing edge during the ejection of K+ ions. The change in dielectric constant of the axon membrane is also discussed, and a possible explanation for the decrease in the excitation threshold of the action potential with an increase in salinity of the external electrolyte is proposed.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Effects of time-dependent ATP consumption caused by neuron firing on ATP concentrations in synaptic boutons containing and lacking a stationary mitochondrion 93%
- Numerical and analytical simulation of the growth of amyloid-β plaques 93%
- Tuning the Pennes Perfusion Rate to Model Large Vessel Cooling Effects in Hepatic Radiofrequency Ablation 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.