Back

Exploring the Potential of Large Language Models in Personalized Diabetes Treatment Strategies

Yang, H.; Li, J.; liu, s.; du, l.; liu, x.; huang, y.; shi, q.; Liu, J.

2023-07-01 health informatics
10.1101/2023.06.30.23292034 medRxiv
Show abstract

This study aims to explore the application of a fine-tuned model-based outpatient treatment support system for the treatment of patients with diabetes, and evaluate its effectiveness and potential value. MethodsThe ChatGLM model was selected as the subject of investigation and trained using the P-tuning and LoRA fine-tuning methods. Subsequently, the fine-tuned model was successfully integrated into the Hospital Information System (HIS). The system generates personalized treatment recommendations, laboratory test suggestions, and medication prompts based on patients basic information, chief complaints, medical history, and diagnosis data. ResultsExperimental testing revealed that the fine-tuned ChatGLM model is capable of generating accurate treatment recommendations based on patient information, while providing appropriate laboratory test suggestions and medication prompts. However, for patients with complex medical records, the models outputs may carry certain risks and cannot fully substitute outpatient physicians clinical judgment and decision-making abilities. The models input data is confined to electronic health record (EHR), limiting the ability to comprehensively reconstruct the patients treatment process and occasionally leading to misjudgments of the patients treatment goals. ConclusionThis study demonstrates the potential of the fine-tuned ChatGLM model in assisting the treatment of patients with diabetes, providing reference recommendations to healthcare professionals to enhance work efficiency and quality. However, further improvements and optimizations are still required, particularly regarding medication therapy and the models adaptability.

Matching journals

The top 5 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.