Genomic Sequencing Surveillance and Antigenic Site Mutations of Respiratory Syncytial Virus in Arizona, USA
Holland, L. A.; Holland, S. C.; Smith, M. F.; Leonard, V. R.; Murugan, V.; Nordstrom, L.; Mulrow, M.; Salgado, R.; White, M.; Lim, E. S.
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We conducted Respiratory Syncytial Virus (RSV) genomic sequencing surveillance of 100 RSV-A and 27 RSV-B specimens collected between November 2022 and April 2023 in Arizona, USA. We identified mutations in the pre-fusion F protein antigenic sites in both RSV-A and RSV-B. Continued genomic surveillance will be important to ensure RSV vaccine effectiveness.
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