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Chiral flows in the separating wall during cell division

Ganguly, V.; Chatterjee, M.; SAIN, A.

2023-03-05 biophysics
10.1101/2023.03.03.531016 bioRxiv
Show abstract

Material flow in the acto-myosin cortex of a cell, during cell division, has been found to be chiral in nature. Here we look for possible signature of such chirality during the growth of the intra-cellular membrane partition which physically divides the cell into two compartments. Many groups have recorded this partition formation phenomenon in C. elegans embryo, in real time, using fluorescent microscopy. We analyze some of these movies using PIV technique in order to search for signatures of chirality in the acto-myosin flow field on this partition. Further, we use standard hydrodynamic theory of active gell to predict possible chiral flow structures in the growing partition. While the flows in the growing annular shaped membrane partition is mainly radially inward, it can also develop non zero azimuthal velocity components due to chirality.

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