Back

GUIFold - A graphical user interface for local AlphaFold2

Kempf, G.; Cavadini, S.

2023-01-20 bioinformatics
10.1101/2023.01.19.521406 bioRxiv
Show abstract

GUIFold is a graphical user interface for the open-source structure prediction pipeline AlphaFold2. A particular emphasis lies on tracking prediction jobs in a database as well as user-friendly submission to queueing systems. GUIFold is built on top of a modified AlphaFold2 pipeline that primarily allows more control of the feature generation step. Additionally, the application provides an evaluation pipeline to rank predictions and visualize confidence metrics. GUIFold can be installed along with AlphaFold2 in a virtual environment and, after initial setup, allows running jobs without particular technical expertise.

Matching journals

The top 1 journal accounts for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.