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Enhanced Neoplasia Detection in Chronic ulcerative colitis: results of the ENDCaP-C Diagnostic accuracy study

2022-12-16 gastroenterology Title + abstract only
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BackgroundChronic ulcerative colitis is an inflammatory condition associated with a pro-neoplastic drive, predisposing to colorectal cancer. Repeated colonoscopy is undertaken to detect preneoplastic change, but cancer diagnosis is still frequently missed. AimsTo determine if a predetermined panel of methylation markers could better risk stratify patients, aiding earlier detection of neoplasia. MethodsENDCaP-C (https://doi.org/10.1186/ISRCTN81826545) was a prospective multicentre test accuracy...

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