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Ultrastructural characterization of a viral RNA and G-protein containing, membranous organelle formed in respiratory syncytial virus infected cells

Vijayakrishnan, S.; Burns, A. M.; Blanchard, E. L.; Spink, M. C.; Gilchrist, J.; Howe, A.; Darrow, M. C.; Harkiolaki, M.; Wu, C.-Y.; Dutch, R. E.; Santangelo, P.; Fearns, R.; Bhella, D.

2022-11-28 microbiology
10.1101/2022.11.28.517999 bioRxiv
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Withdrawal statementThe authors have withdrawn their manuscript because since deposition of this preprint, they have become aware of the possibility that the findings reported may be an artefact. Carter et al. (J Struct Biol 2018 Jan;201(1):15-25. doi: 10.1016/j.jsb.2017.10.009) have reported that multilamellar bodies exhibit autofluorescence under cryogenic conditions. Thus, there is a possibility that stress induced by virus infection may stimulate formation of the features reported in this article, and autofluorescence, rather than specific labelling led them to identify the puncta as compartments containing RSV proteins or genomes. They are working to address these issues. Therefore, the authors do not wish this work to be cited as reference for the project. If you have any questions, please contact the corresponding author.

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