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The Blood-Brain Barrier in Bipolar Disorders: A Systematic Review

2022-11-11 psychiatry and clinical psychology Title + abstract only
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BackgroundBipolar disorders (BD) are chronic, debilitating disorders. Our understanding of the pathogenesis and functional biomarkers in BD remains limited. The blood-brain barrier (BBB), a highly selective, protective physical barrier which separates the central nervous system from the peripheral circulation, has been increasingly investigated in the BD. This systematic review aimed to assess the relationship between BD and markers of BBB dysfunction. MethodsStudies were identified in PubMed a...

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