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The possibility of anesthesia stimulated by a train of current pulses

Shneider, M.; Pekker, M.

2022-10-17 bioengineering
10.1101/2022.10.13.512150 bioRxiv
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This paper considers a simple theoretical model of blocking the passage of signals (action potentials) from sensory neurons and thereby effecting anesthesia without the use of anesthetics as a result of a sequence of unipolar current pulses generated by an external source. The proposed model allows the selection of parameters and the required frequency of the repetition of current pulses for the possible implementation of anesthesia depending on the electrical characteristics of the skin and the conductivity of the saline solution in which the myelinated nerve fibers are located.

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