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NetLCP: An R package for prioritizing combinations of regulatory elements in the heterogeneous network with variant 'switches' detection

ran, M.; Xu, J.

2022-10-08 bioinformatics
10.1101/2022.10.06.511229 bioRxiv
Show abstract

Numerous independent networks of regulatory elements, including lncRNA, circRNA and pathway, have been developed to crucial roles in computational systems biology. Crosstalks among those networks as a bridge to build and decode heterogeneous networks from multidimensional biological knowledge, aids to highlight regulatory elements. And combinations of regulatory elements (CREs) in the local area of heterogeneous network have been a hot issue due to its crucial role in biological processes. We introduce NetLCP, an R package with command and shiny-based GUI modes, for prioritizing CREs with variant switches detection. Availability and implementationThe NetLCP package and documentations are freely available at https://github.com/mortyran/NetLCP. Supplementary informationSupplementary data are available online

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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.