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Brain Structural Differences in Adults Reporting Localized Chronic Pains Mediate Risk for Suicidal Behaviors

2022-10-06 pain medicine Title + abstract only
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BackgroundChronic pain is a global health priority. Mapping pain occurring at different body sites, and variability in brain circuitry related to widespread chronic pain, can elucidate nuanced roles of the central nervous system underlying chronic pain conditions. Chronic pain triples suicide risk; however, whether brain circuitry can inform this risk relationship has not been investigated. Methods11,298 participants (mean age: 64 years (range: 58-70), 55% female) with brain MRI from the UK Bio...

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