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Deep Learning Integration of Chest CT Imaging and Gene Expression Identifies Novel Aspects of COPD
2022-09-27
respiratory medicine
Title + abstract only
View on medRxiv
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RationaleChronic obstructive pulmonary disease (COPD) is characterized by pathologic changes in the airways, lung parenchyma, and persistent inflammation, but the links between lung structural changes and patterns of systemic inflammation have not been fully described. ObjectivesTo identify novel relationships between lung structural changes measured by chest computed tomography (CT) and systemic inflammation measured by blood RNA sequencing. MethodsCT scan images and blood RNA-seq gene expres...
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