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A Web-based Software Resource for Interactive Analysis of Multiplex Tissue Imaging Datasets

Creason, A. L.; Watson, C.; Gu, Q.; Persson, D.; Sargent, L. L.; Chen, Y.-A.; Lin, J.-R.; Sivagnanam, S.; Wünnemann, F.; Nirmal, A. J.; Chin, K.; Feiler, H. S.; Coussens, L. M.; Schapiro, D.; Grüning, B. A.; Sorger, P. K.; Sokolov, A.; Goecks, J.

2022-12-03 bioinformatics
10.1101/2022.08.18.504436 bioRxiv
Show abstract

Highly multiplexed tissue imaging (MTI) are powerful spatial proteomics technologies that enable in situ single-cell characterization of tissues. However, analysis and visualization of MTI datasets remains challenging, and we developed the Galaxy-ME software hub to address this challenge.Galaxy-ME is a web-based, interactive software hub that enables end-to-end analysis and visualization of MTI datasets and is accessible to everyone. To demonstrate its utility, Galaxy-ME was used to analyze datasets obtained from multiple MTI assays and evaluate assay concordance in both normal and cancerous tissues. Galaxy-ME is a publicly available web resource.

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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.