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A fully phased interspecific grapevine rootstock genome sequence representing V. riparia and V. cinerea and allele-aware annotation of the phylloxera resistance locus Rdv1

Frommer, B.; Hausmann, L.; Holtgraewe, D. L.; Viehoever, P.; Huettel, B.; Reinhardt, R.; Toepfer, R.; Weisshaar, B.

2022-07-27 genomics
10.1101/2022.07.07.499180 bioRxiv
Show abstract

The phylloxera resistant rootstock cultivar Borner is an interspecific hybrid derived from Vitis riparia and V. cinerea and a valuable resource for Vitis disease resistances. We created a fully phased, high-quality Borner genome sequence named BoeRC using long PacBio reads. Comprehensive gene annotation of both Borner haplotypes, designated BoeRip and BoeCin, was applied to describe the phylloxera resistance locus Rdv1. Using a mapping population derived from a susceptible V. vinifera breeding line and Borner, the Rdv1 locus was further delimited. Rdv1, which is derived from V. cinerea and included in the haplotype BoeCin, was compared with sequences of phylloxera-susceptible and phylloxera-tolerant cultivars. Between flanking regions that display high synteny, we detected and precisely characterized a diverse sequence region that covers between 202 to 403 kbp in different haplotypes. In BoeCin, five putative disease resistance genes were identified that represent likely candidates for conferring resistance to phylloxera.

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