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In Vivo and Phantom Repeatability of Diffusion-Weighted MRI Sequences on 1.5T MRI-Linear Accelerator (MR-Linac) and MR Simulator Devices for Head and Neck Cancers: Results from a Prospective R-IDEAL Stage 2a Evaluation of Tumor and Normal Tissue Apparent Diffusion Coefficients as Quantitative Imaging Biomarkers

2022-05-29 radiology and imaging Title + abstract only
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IntroductionDiffusion-weighted imaging (DWI) on MRI-linear accelerator (MR-linac) systems can potentially be used for monitoring treatment response and adaptive radiotherapy in head and neck cancers (HNC) but requires extensive validation. We perform technical validation to compare six total DWI sequences on an MR-linac and MR simulator (MR sim) in patients, volunteers, and phantoms. MethodsTen human papillomavirus-positive oropharyngeal cancer patients and ten volunteers underwent DWI on a 1.5...

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