Back
#1
14.3%
Top 0.3%
14.3%
Top 1%
11.6%
Top 9%
10.8%
Top 2%
5.8%
Top 0.6%
4.9%
Top 64%
4.1%
Top 6%
2.1%
Top 5%
1.9%
Top 1%
1.9%
Top 3%
1.9%
Top 2%
1.9%
Top 9%
1.5%
Top 3%
1.5%
Top 6%
1.5%
Top 95%
1.5%
Top 35%
1.3%
Top 4%
1.2%
Top 10%
1.2%
Top 5%
1.0%
Top 1%
0.9%
Top 5%
0.9%
Top 7%
0.7%
Top 3%
0.7%
Top 5%
0.7%
Top 5%
0.7%
Top 6%
0.7%
Top 15%
0.7%
Top 19%
0.7%
Top 10%
0.7%
Directional anchor genes refine polygenic informed treatment selection in schizophrenia and bipolar disorder
2022-03-22
psychiatry and clinical psychology
Title + abstract only
View on medRxiv
Show abstract
Genetically informed drug development and repurposing is an attractive prospect for improving outcomes in patients with psychiatric illness; however, the effectiveness of these endeavours can be confounded by heterogeneity. In this study, we propose a novel approach that links interventions implicated by disorder-associated genetic risk, at the population level, to a framework that can target these compounds to individuals. Specifically, results from genome-wide association studies are integrate...
Predicted journal destinations
1
Biological Psychiatry
36 training papers
2
Molecular Psychiatry
84 training papers
3
Translational Psychiatry
94 training papers
4
Nature Communications
483 training papers
5
Psychological Medicine
52 training papers
6
Schizophrenia Bulletin
21 training papers
7
Scientific Reports
701 training papers
8
Nature Genetics
72 training papers
9
Journal of Affective Disorders
72 training papers
10
Biological Psychiatry Global Open Science
23 training papers
11
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
27 training papers
12
Neuropsychopharmacology
29 training papers
13
Proceedings of the National Academy of Sciences
100 training papers
14
Nature
58 training papers
15
Frontiers in Psychiatry
56 training papers
16
PLOS ONE
1737 training papers
17
eLife
262 training papers
18
Brain, Behavior, and Immunity
35 training papers
19
NeuroImage: Clinical
77 training papers
20
Psychiatry Research
33 training papers
21
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
15 training papers
22
Journal of Psychiatric Research
22 training papers
23
Science
46 training papers
24
Journal of Child Psychology and Psychiatry
18 training papers
25
The British Journal of Psychiatry
21 training papers
26
BJPsych Open
24 training papers
27
Science Advances
52 training papers
28
PLOS Computational Biology
141 training papers
29
Nature Medicine
88 training papers
30
Human Brain Mapping
53 training papers