SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
Hale, V. L.; Dennis, P. M.; McBride, D. S.; Nolting, J. M.; Madden, C.; Huey, D.; Ehrlich, M.; Grieser, J.; Winston, J. A.; Lombardi, D.; Gibson, S.; Saif, L.; Killian, M. L.; Lantz, K.; Tell, R. M.; Torchetti, M. K.; Robbe-Austerman, S.; Nelson, M. I.; Faith, S. A.; Bowman, A.
10.1101/2021.11.04.467308 bioRxivShow abstract
Human-to-animal spillover of SARS-CoV-2 virus has occurred in a wide range of animals, but thus far, the establishment of a new natural animal reservoir has not been detected. Here, we detected SARS-CoV-2 virus using rRT-PCR in 129 out of 360 (35.8%) free-ranging white-tailed deer (Odocoileus virginianus) from northeast Ohio (USA) sampled between January-March 2021. Deer in 6 locations were infected with at least 3 lineages of SARS-CoV-2 (B.1.2, B.1.596, B.1.582). The B.1.2 viruses, dominant in Ohio at the time, spilled over multiple times into deer populations in different locations. Deer-to-deer transmission may have occurred in three locations. The establishment of a natural reservoir of SARS-CoV-2 in white-tailed deer could facilitate divergent evolutionary trajectories and future spillback to humans, further complicating long-term COVID-19 control strategies. One-Sentence SummaryA significant proportion of SARS-CoV-2 infection in free-ranging US white-tailed deer reveals a potential new reservoir.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Respiratory shedding of infectious SARS-CoV-2 Omicron XBB.1.41.1 lineage with increased evolutionary rate among captive white-tailed deer 98%
- Novel Hendra virus variant detected by sentinel surveillance of Australian horses. 95%
- Intercontinental movement of H5 2.3.4.4 Highly Pathogenic Avian Influenza A(H5N1) to the United States, 2021 94%
Similar papers in this journal
- Novel Adomaviruses Associated with Blotchy Bass Syndrome in Black Basses (Micropterus spp.) 93%
- Coronavirus testing indicates transmission risk increases along wildlife supply chains for human consumption in Viet Nam, 2013-2014 93%
- SARS-CoV-2 detection and genomic sequencing from hospital surface samples collected at UC Davis 92%
Similar papers in this journal
- Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 96%
- Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City 95%
- Feline leukemia virus (FeLV) endogenous and exogenous recombination events result in multiple FeLV-B subtypes during natural infection 95%
Similar papers in this journal
- Multiple spillovers and onward transmission of SARS-Cov-2 in free-living and captive White-tailed deer 98%
- SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus) 98%
- White-tailed deer (Odocoileus virginianus) may serve as a wildlife reservoir for nearly extinct SARS-CoV-2 variants of concern 97%
Similar papers in this journal
- First isolation and genetic characterization of Puumala orthohantavirus strains from France 92%
- How bank vole-PUUV interactions influence the eco-evolutionary processes driving nephropathia epidemica epidemiology: An experimental and genomic approach. 92%
- Temporal dynamics of cytokine, leukocyte, and whole blood transcriptome profiles of pigs infected with African swine fever virus 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.