Orfamide-A-mediated bacterial-algal interactions involve specific Ca2+ signalling pathways
Hou, Y.; Bando, Y.; Carrasco Flores, D.; Hotter, V. S.; Schiweck, B.; Arndt, H.-D.; Mittag, M.
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The antagonistic bacterium Pseudomonas protegens secretes the cyclic lipopeptide orfamide A, which triggers a Ca2+ signal, causing the deflagellation of the green microalga Chlamydomonas reinhardtii. By investigating targeted synthetic orfamide A variants and inhibitors, we found that at least two Ca2+-signalling pathways and TRP channels are involved in this response.
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