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Genomic rearrangements have consequences for introgression breeding as revealed by genome assemblies of wild and cultivated lentil species

Ramsay, L.; Koh, C. S.; Kagale, S.; Gao, D.; Kaur, S.; Haile, T.; Gela, T. S.; Chen, L.-A.; Cao, Z.; Konkin, D. J.; Toegelova, H.; Dolezel, J.; Rosen, B. D.; Stonehouse, R.; Humann, J. L.; Main, D.; Coyne, C. J.; McGee, R. J.; Cook, D. R.; Penmetsa, R. V.; Vandenberg, A.; Chan, C.; Banniza, S.; Edwards, D.; Bayer, P. E.; Batley, J.; Udupa, S. M.; Bett, K. E.

2021-07-24 plant biology
10.1101/2021.07.23.453237 bioRxiv
Show abstract

Understanding the genomic relationship between wild and cultivated genomes would facilitate access to the untapped variability found in crop wild relatives. We developed genome assemblies of a cultivated lentil (Lens culinaris) as well as a wild relative (L. ervoides). Comparative analyses revealed large-scale structural rearrangements and additional repetitive DNA in the cultivated genome, resulting in regions of reduced recombination, segregation distortion and permanent heterozygosity in the offspring of a cross between the two species. These novel findings provide plant breeders with better insight into how best to approach accessing the novel variability available in wild relatives.

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