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Stable IgG-antibody levels in patients with mild SARS-CoV-2 infection

Akerlund, T.; Zakikhany, K.; Lofstrom, C.; Lindmark, E.; Kallberg, H.; Elofsson, U.; Cedebrant, K.; Nygren, E.; Kallin, A.; Lagerqvist, N.; Nilsson, P.; Hober, S.; Ridderstad Wollberg, A.; Bjorndal, A.

2021-06-18 infectious diseases
10.1101/2021.06.16.21258960 medRxiv
Show abstract

More knowledge regarding persistence of antibody response to SARS-CoV-2 infections in the general population with mild symptoms is needed. We measured and compared levels of SARS-CoV-2 spike- and nucleocapsid-specific IgG-antibodies in serum samples from 145 laboratory-confirmed COVID-19 cases and 324 non-cases. The IgG-antibody levels against the spike protein in cases were stable over the time-period studied (14 to 256 days), while antibody levels against the nucleocapsid protein decreased over time.

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