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Detection of Junctional Ectopic Tachycardia by Central Venous Pressure

Tan, X.; Dai, Y.; Humayum, A. I.; Chen, H.; Allen, G. I.; Jain, P.

2021-04-04 bioinformatics
10.1101/2021.04.02.438266 bioRxiv
Show abstract

Central venous pressure (CVP) is the blood pressure in the venae cavae, near the right atrium of the heart. This signal waveform is commonly collected in clinical settings, and yet there has been limited discussion of using this data for detecting arrhythmia and other cardiac events. In this paper, we develop a signal processing and feature engineering pipeline for CVP waveform analysis. Through a case study on pediatric junctional ectopic tachycardia (JET), we show that our extracted CVP features reliably detect JET with comparable results to the more commonly used electrocardiogram (ECG) features. This machine learning pipeline can thus improve the clinical diagnosis and ICU monitoring of arrhythmia. It also corroborates and complements the ECG-based diagnosis, especially when the ECG measurements are unavailable or corrupted.

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