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Phenotype Risk Scores: moving beyond cases and controls to classify psychiatric disease in hospital-based biobanks.
2021-01-26
psychiatry and clinical psychology
Title + abstract only
View on medRxiv
Show abstract
Current phenotype classifiers for large biobanks with coupled electronic health records EHR and multi-omic data rely on ICD-10 codes for definition. However, ICD-10 codes are primarily designed for billing purposes, and may be insufficient for research. Nuanced phenotypes composed of a patients experience in the EHR will allow us to create precision psychiatry to predict disease risk, severity, and trajectories in EHR and clinical populations. Here, we create a phenotype risk score (PheRS) for m...
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