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Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink(C) electrodes

Zakashansky, J. A.; Imamura, A. H.; Salgado, D. F.; Romero Mercieca, H. C.; Aguas, R. F. L.; Lao, A. M.; Pariser, J. M.; Arroyo-Curras, N.; Khine, M.

2020-11-16 infectious diseases
10.1101/2020.11.14.20231811
Show abstract

Using the childrens toy, Shrinky-Dink (C), we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 0.1 fg mL-1 of the S1 subunit of the spike protein.

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