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Prevalence of IgG antibodies against the severe acute respiratory syndrome coronavirus-2 among healthcare workers in Tennessee during May and June, 2020

Rebeiro, P. F.; Levinson, K. J.; Jolly, L.; Kassens, E.; Dizikes, G. J.; Steece, R. S.; Metzger, D. C.; Loos, M.; Buchheit, R.; Duncan, L. D.; Rolando, L. A.; Schmitz, J.; Hart, H. A.; Aronoff, D. M.; Tennessee COVID-19 Serology Study Team,

2020-11-16 infectious diseases
10.1101/2020.11.12.20230912 medRxiv
Show abstract

SARS-CoV-2 seroprevalence was low (<1%) in this large population of healthcare workers (HCWs) across the state of Tennessee (n=11,787) in May-June 2020. Among those with PCR results, 81.5% of PCR and antibody test results were concordant. SARS-CoV-2 seroprevalence was higher among HCWs working in high-community-transmission regions and among younger workers. ImportanceThese results may be seen as a baseline assessment of SARS-CoV-2 seroprevalence among HCWs in the American South during a period of growth, but not yet saturation, of infections among susceptible populations. In fact, this period of May-June 2020 was marked by the extension of renewed and sustained community-wide transmission after mandatory quarantine periods expired in several more populous regions of Tennessee. Where community transmission remains low, HCWs may still be able to effectively mitigate SARS-CoV-2 transmission, preserving resources for populations at high risk of severe disease, and these sorts of data help highlight such strategies.

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