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Dynamic multi-OMICs of glioblastoma reveal sensitivity to neddylation inhibition dependent on nuclear PTEN and DNA replication pathways

Ferdosi, S. R.; Taylor, B.; Lee, M.; Peng, S.; Tang, N.; Bybee, R.; Reid, G.; Hartmen, L.; Garcia-Mansfield, K.; Sharma, R.; Pirrotte, P.; Furnari, F.; Dhruv, H. D.; Berens, M. E.

2020-07-21 cancer biology
10.1101/2020.07.21.212571 bioRxiv
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Withdrawal StatementThe authors have withdrawn their manuscript because the reported synergy of TOP2A inhibitors plus MLN4924 proved to be untrue (not reproducible). Therefore, the authors do not wish this work to be cited as reference for the project. If you have any questions, please contact the corresponding author (mberens@tgen.org).

Matching journals

The top 11 journals account for 50% of the predicted probability mass.

1
Molecular Oncology
○ 55 papers in training set
Top 0.1%
12.6%
Similar papers in this journal
2
EMBO Molecular Medicine
○ 95 papers in training set
Top 0.1%
12.0%
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3
Frontiers in Oncology
○ 103 papers in training set
Top 0.6%
5.5%
Similar papers in this journal
4
Neuro-Oncology
◐ 36 papers in training set
Top 0.2%
4.9%
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5
Neoplasia
○ 23 papers in training set
Top 0.1%
2.7%
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6
iScience
○ 1154 papers in training set
Top 11%
2.4%
7
Cell Reports
○ 1498 papers in training set
Top 16%
2.1%
8
Cell Communication and Signaling
○ 51 papers in training set
Top 0.3%
2.1%
9
Nature Communications
○ 5641 papers in training set
Top 41%
2.1%
10
Acta Neuropathologica Communications
○ 89 papers in training set
Top 0.9%
2.1%
11
Molecular Cancer
○ 16 papers in training set
Top 0.1%
1.9%
50% of probability mass above
12
Journal of Experimental & Clinical Cancer Research
○ 25 papers in training set
Top 0.3%
1.7%
13
Life Science Alliance
● 285 papers in training set
Top 3%
1.7%
14
npj Precision Oncology
○ 53 papers in training set
Top 0.8%
1.7%
15
Cell Death Discovery
○ 58 papers in training set
Top 0.6%
1.7%
16
eBioMedicine
○ 183 papers in training set
Top 3%
1.7%
17
PLOS ONE
● 5266 papers in training set
Top 49%
1.4%
18
Cells
○ 249 papers in training set
Top 4%
1.4%
19
British Journal of Cancer
○ 49 papers in training set
Top 0.9%
1.3%
20
Cell Reports Medicine
○ 153 papers in training set
Top 3%
1.3%
21
EMBO Reports
○ 263 papers in training set
Top 5%
1.1%
22
Genome Medicine
○ 183 papers in training set
Top 4%
1.1%
23
Neuro-Oncology Advances
◐ 25 papers in training set
Top 0.3%
1.1%
24
Scientific Reports
○ 3612 papers in training set
Top 62%
1.1%
25
Nucleic Acids Research
◐ 1281 papers in training set
Top 12%
1.0%
26
Cancers
○ 213 papers in training set
Top 4%
1.0%
27
Cell Death & Disease
147 papers in training set
Top 3%
0.9%
28
BMC Biology
○ 265 papers in training set
Top 5%
0.9%
29
Journal of Neuroinflammation
○ 61 papers in training set
Top 1%
0.9%
30
npj Systems Biology and Applications
○ 125 papers in training set
Top 2%
0.9%

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.