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Optimal Size of COVID-19 Testing Pools

cohen, j. D.

2020-07-22 health economics
10.1101/2020.07.20.20158436 medRxiv
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This research note investigates the optimal size of pools for pooled, COVID-19 testing when positive pools will be followed up by individual tests of pool members. Formulae for the optimum are derived and provided. The analysis indicates that O_LIoptimal pool sizes are unlikely to exceed about 20 individuals in realistic situations, C_LIO_LIoptimal pool size is influenced by prevalence in the population and the extent to which infection is clustered within the population, and, C_LIO_LIpools are most efficiently comprised of people with homogeneous risk, with heterogeneity across pools. C_LI

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