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The Homo-Edit Distance Problem

Brand, M.; Tran, N. K.; Spohr, P.; Schrinner, S.; Klau, G. W.

2020-06-03 bioinformatics
10.1101/2020.05.27.118273 bioRxiv
Show abstract

We consider the homo-edit distance problem, which is the minimum number of homo-deletions or homo-insertions to convert one string into another. A homo-insertion is the insertion of a string of equal characters into another string, while a homo-deletion is the inverse operation. We show how to compute the homo-edit distance of two strings in polynomial time: We first demonstrate that the problem is equivalent to computing a common subsequence of the two input strings with a minimum number of homo-deletions and then present a dynamic programming solution for the reformulated problem. 2012 ACM Subject ClassificationApplied computing [->] Bioinformatics; Applied computing [->] Molecular sequence analysis; Theory of computation [->] Dynamic programming

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