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Routine Early Antibiotic use in SymptOmatic preterm Neonates (REASON): a prospective randomized controlled trial.

2020-04-22 pediatrics Title + abstract only
View on medRxiv
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ObjectiveWe aim to assess the feasibility of a pragmatic randomized trial of antibiotics vs. no antibiotics in symptomatic premature infants after birth. Most premature infants are exposed to antibiotics after birth without evidence of benefit or harm for this practice. No study to date has attempted to randomize premature infants to antibiotics vs no antibiotics after birth. Study DesignInfants <33 weeks gestation admitted to the University of Florida Neonatal Intensive Care Unit were assigned...

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