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Multiple known and a novel parvovirus associated with an outbreak of feline diarrhea and vomiting

Li, Y.; Gordon, E.; Idle, A.; Altan, E.; Seguin, M. A.; Estrada, M.; Deng, X.; Delwart, E.

2020-03-25 microbiology
10.1101/2020.03.24.005876 bioRxiv
Show abstract

An unexplained outbreak of feline diarrhea and vomiting, negative for common enteric viral and bacterial pathogens, was subjected to viral metagenomics and PCR. We characterized from fecal samples the genome of a novel chapparvovirus we named fechavirus that was shed by 8/17 affected cats and different feline bocaviruses shed by 9/17 cats. Also detected were nucleic acids from attenuated vaccine viruses, members of the normal feline virome, viruses found in only one or two cases, and viruses likely derived from ingested food products. Epidemiological investigation of disease signs, time of onset, and transfers of affected cats between three facilities support a possible role for this new chapparvovirus in a highly contagious feline diarrhea and vomiting disease.

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