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Buprenorphine treatment of opioid dependence: analysis of individual patient data

2020-03-20 addiction medicine Title + abstract only
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BackgroundThe efficacy and safety of buprenorphine alone and in combination with naloxone for treatment of opioid dependence were evaluated in Federally-sponsored randomized clinical trials. Meta-analysis of pooled individual participant data provides an opportunity to identify multiple predictors of buprenorphine treatment outcome. MethodsWe selected six buprenorphine efficacy and safety trials from NIDAs Data Share database for analysis. Treatment, sociodemographic, and drug use history varia...

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