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Duration of viral detection in throat and rectum of a patient with COVID-19

Tan, L. V.; Ngoc, N. M.; That, B. T. T.; Uyen, L. T. T.; Hong, N. T. T.; Dung, N. T. P.; Nhu, L. N. T.; Thanh, T. T.; Man, D. N. H.; Phong, N. T.; Hien, T. T.; Truong, N. T.; Thwaites, G.; Chau, N. V. V.

2020-03-16 infectious diseases
10.1101/2020.03.07.20032052 medRxiv
Show abstract

The rapid spread of coronavirus disease 2019 (COVID-19) raises concern about a global pandemic. Knowledge about the duration of viral shedding remains important for patient management and infection control. We report the duration of viral detection in throat and rectum of a COVID-19 patient treated at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam. Despite clinical recovery, SARS-CoV-2 RNA remained detectable by real time RT-PCR in throat and rectal swabs until day 11 and 18 of hospitalization, respectively. Because live SARS-CoV-2 has been successfully isolated from a stool sample from a COVID-19 patient in China, the results demonstrate that COVID-19 patients may remain infectious for long periods, and fecal-oral transmission may be possible. Therefore, our finding has important implications for infection control.

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