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Whole Slide Preview Image Segmentation and Setup for Digital Pathology Scanners

Hosseini, M. S.; Lee, D.; Gershanik, D.; Lee, D.; Damaskinos, S.; Plataniotis, K. N.

2020-02-26 pathology
10.1101/2020.02.24.963645 bioRxiv
Show abstract

The problem of tissue finding is of special interest in automating WSI scanners where it decomposes the preview image of tissue glass slides into a simplified and abstract level of localization and identification to setup WSI scanner for high-resolution scan. Prior to such scanning, a preview image is captured to calibrate the scanners parameters. Scan parameters such as focus depth and scan region are determined using a tissue finding software package. This paper introduces a series of pipelines (e.g. binary mask segmentation, tissue/artifact classification, region-of-interest allocation) to automate tissue preview segmentation in both brightfield and darkfield microscopy.

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